Pharmacological effects of Ginseng in the Liver and Diabetes
The pharmacological effects of ginseng are mostly used therapeutically, ie, metabolites (such as ginsenosides) that affect a living system in order to treat a certain condition. There are several applications of ginsenosides in treatments of diseases and human conditions. Among them are anticancer effects, antidiabetics, antioxidants, among many others. Here are some areas where ginseng exerts its positive effects: Liver In this organ ginseng has impacts in the fight against diseases caused by hepatotoxic agents and hepatitis. In the first case, the simple use of ginseng extracts with dietary honey can exert a synergetic effect to combat this type of diseases. The use of high doses of Paracetamol can lead to liver damage due to the effect of cytochrome P450 2E1 on acetaminophen (paracetamol), which converts it to N-acetyl-p-benzoquinone (hepatotoxin). Ginseng exerts a hepatoprotective effect due to Rg3 that inhibits the cytochrome in question (El Denshary et ...