Discovery and Study of Modified Genes
Domesticated genes can be identified and isolated by using technologies as quantitative trait locus ( QTL) analysis, genome-wide association studies (GWAS) and whole genome resequencing studies. GWAS identifies significant associations between genes and phenotypic traits by using markers, focusing on single-nucleotide polymorphisms (SNPs) in the genome and linkage disequilibrium to provide full coverage (Meyer and Purugganan, 2013) . Quantitative Trait Locus (QTL) mapping (or Linkage mapping) is a technique that is among the first used in the study of domesticated traits (Doebley et al., 2006; Gross and Olsen, 2010). According to Meyer and Purugganan (2013), QTL is defined as a “genomic region with a gene (or multiple linked genes) that contains mutations which result in phenotypic variation in populations” (Meyer and Purugganan, 2013). And the main goal of the QTL mapping is to help study less understood phenotypes by characterizing (number, location, and impact) the det